Icosapent ethyl reduces ischemic events in patients with hypertriglyceridemia
نویسندگان
چکیده
منابع مشابه
Icosapent ethyl for the treatment of severe hypertriglyceridemia
Hypertriglyceridemia is a highly prevalent lipid abnormality and it is associated with atherosclerosis, with a growing body of evidence linking elevated triglycerides (TGs) with cardiovascular disease. The current major omega-3 polyunsaturated fatty acids, eicosapentaenoic acid (EPA)/docosahexaenoic acid (DHA) combination, lowers serum TGs while often increasing levels of low-density lipoprotei...
متن کاملANTI CARDIOLIPIN ANTIBODIES IN PATIENTS WITH ISCHEMIC EVENTS
To determine the presence of anticardiolipin (aCL) antibodies in patients with ischemic events, we designed a case-control study. We studied 33 patients with unstable angina, 33 male patients with myocardial infarction and 34 control subjects with no evidence of ischemic heart disease. Plasma samples were assessed for IgG anticardiolipin antibodies by enzyme-linked immunosorbent assay (ELI...
متن کاملRationale and design of REDUCE‐IT: Reduction of Cardiovascular Events with Icosapent Ethyl–Intervention Trial
Residual cardiovascular risk persists despite statins, yet outcome studies of lipid-targeted therapies beyond low-density lipoprotein cholesterol (LDL-C) have not demonstrated added benefit. Triglyceride elevation is an independent risk factor for cardiovascular events. High-dose eicosapentaenoic acid (EPA) reduces triglyceride-rich lipoproteins without raising LDL-C. Omega-3s have postulated p...
متن کاملanti cardiolipin antibodies in patients with ischemic events
to determine the presence of anticardiolipin (acl) antibodies in patients with ischemic events, we designed a case-control study. we studied 33 patients with unstable angina, 33 male patients with myocardial infarction and 34 control subjects with no evidence of ischemic heart disease. plasma samples were assessed for igg anticardiolipin antibodies by enzyme-linked immunosorbent assay (elisa). ...
متن کاملHypertriglyceridemia and ischemic stroke.
There are no conclusive data regarding the association between dyslipidemia and the risk of ischemic stroke (IS). Clinical investigations have primarily focused on the association between elevated levels of low-density lipoprotein cholesterol and low levels of high-density lipoprotein cholesterol as stroke risk factors. Much less scientific attention has been aimed at elevated levels of triglyc...
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ژورنال
عنوان ژورنال: Pharmacy Today
سال: 2019
ISSN: 1042-0991
DOI: 10.1016/j.ptdy.2019.03.005